Cefazoxime, cefixime, cefotaxime, ceftazidime, ceftazidime, and cefsulodine are cephalosporins that do not cause disulfiram. Because these cephalosporins do not contain methylthiotetrazole groups, they do not react chemically with alcohol, so they generally do not cause a disulfiram reaction, whereas many cephalosporins, such as cefoperazone, cefaclor, and cefazolin, contain methylthiotetrazole groups, which can react with alcohol, so you should not drink alcohol after taking these drugs. Disulfiram reaction refers to the chemical reaction between antibiotics and alcohol mixing after the discomfort, will make the human body feel a strong sense of discomfort, serious cases will be life-threatening, so in taking cephalosporins or penicillin drugs is prohibited to drink.