Frequent waking up in the second half of the night may be caused by physiological reasons such as neurodevelopmental insufficiency, or pathological reasons such as heart disease, respiratory disease and other reasons. 1. Physiological reasons: the baby’s neurodevelopment is not yet perfect, can cause the baby to wake up frequently in the second half of the night, generally do not need special treatment. 2. Pathological causes: such as congenital heart disease and other causes can cause breathing difficulties, frequent waking up in the second half of the night; such as pneumonia and other respiratory diseases can affect the lungs breathing, resulting in frequent waking up in the second half of the night. Parents are advised to bring their children to the hospital in time to clarify the cause, if treatment is needed, standardized treatment should be carried out under the guidance of the doctor to avoid delaying the condition.