CA199, also known as Glyco Antigen 199, can be elevated by gallstones, but usually the elevation is low and does not last long. CA199 can be distributed in the pancreas, gallbladder, liver, intestines and other parts of normal fetus, and normal adult pancreas, bile duct epithelium and other parts of the body, so monitoring its value level can be a variety of gastrointestinal diseases, tumors and so on, have a certain hint, diagnostic effect. Its normal value in serum is less than <37.00u/ml, if its value is elevated, it can be caused by a variety of reasons, and need to carry out further examination. If there are gallstones in the body, it is possible to cause CA199 to be elevated, and the diagnosis should be clarified after further abdominal ultrasound, transendoscopic retrograde cholangiopancreatography (ERCP) and other examinations. Other tests should also be performed to clarify whether there are other causes of CA199 elevation, such as cholecystitis, hepatitis, pancreatic cancer, colorectal cancer, and so on.