There is no fastest clinical treatment for sweaty palms and feet, which may be caused by physiological factors and generally does not require treatment. It may also be caused by hyperthyroidism, hypoglycemia and other diseases, which can be treated by medication and surgery. 1. Physiological factors: emotional excitement or strenuous exercise, etc., will lead to sympathetic nervous excitement, thus appearing the phenomenon of sweaty palms and feet, generally do not need treatment, calm down, reduce the activities, most of the sweaty palms and feet can be relieved on their own. 2. Hyperthyroidism: Hyperthyroidism may also lead to sweating palms and feet, you can take methimazole tablets, propranolol hydrochloride tablets and other drugs under the guidance of the doctor to treat. If there is drug treatment is ineffective or the disease is suspected to be malignant and other phenomena, you can carry out sub-total thyroidectomy, total thyroidectomy and other surgeries. 3. Hypoglycemia: When hypoglycemia patients have sweaty palms and feet, they can take glucose orally to improve the situation, and if necessary, they can also be treated with intravenous glucose solution. If hypoglycemia is caused by insulinoma, surgery is needed to remove the tumor. People with sweaty palms and feet are recommended to be admitted to the hospital for examination and standardized treatment according to the etiology after physiological factors are ruled out.