The main causes of high cysteine are genetic factors, nutritional factors lifestyle, age and gender, diseases and medications, etc. The main treatments are lifestyle interventions and nutritional therapy. It is recommended to consult a specialist and follow the doctor’s instructions for medication. Cysteine mainly refers to the blood homocysteine, through the hematological examination clearly, hyperhomocysteinemia is a risk factor for a variety of chronic diseases. 1. Causes: Inactivation of certain enzymes due to gene mutation, excessive consumption or insufficient intake of folic acid and vitamin B6 due to smoking and alcohol consumption, increasing age, diseases such as renal dysfunction and injuries, and medications such as anti-epileptic drugs can increase blood homocysteine levels, and men are more likely to be homocysteine-prone than women. 2.Treatment: (1) Healthy lifestyle intervention: develop a good lifestyle, stop smoking and limit alcohol, strengthen nutrition, and exercise appropriately. (2) Nutritional treatment: folic acid tablets, vitamin B12, vitamin B6, natural betaine, choline and many other drugs, which can be used singly or in combination. Studies have found that compound nutritional supplements to reduce homocysteine are more effective than simple supplementation of folic acid, and natural betaine+folic acid+vitamin B6+assistive nutrients are often used, and they can be supplemented according to the genetic precision as well. Natural betaine + folic acid + vitamin B2 + vitamin B6 + vitamin B12 is recommended for hypertension. Elevated blood homocysteine is detected and it is recommended to receive standardized treatment in time.