For the location of the liver pain described by the patient, if there is a space-occupying lesion in the liver parenchyma, or if the liver parenchyma is enlarged, which causes the patient’s hepatic envelope to be tense, it is possible. In this case, the patient may experience swelling and discomfort or vague pain in the right upper abdomen, right back, and right shoulder. First of all, the patient needs to check the ultrasound of the upper abdomen to see the size of the liver. Next, the doctor should do a physical examination to see if the enlarged liver can be palpated under the rib margins, and whether the hardness of the liver is mild, moderate, or severe. If the patient has an enlarged liver, it is important to actively consider the cause of the enlarged liver, whether it is due to hepatic stasis or due to the acute phase of acute hepatitis. Whether the patient has space-occupying lesions in the liver, if the tumor is relatively large and causes tension in the hepatic pericardium, it can also cause the patient’s right upper abdominal pain and discomfort as well as distension and discomfort. In addition, the patient’s right upper abdominal distension and discomfort, and cholecystitis combined with gallbladder stones need to be identified.