It is recommended to consult the rheumatology and immunology department in time to control the existing symptoms and stop the progression of the disease through local treatment, systemic medication and surgical treatment as prescribed by the doctor. Leukemia, or Behçet’s syndrome, is a chronic systemic vascular inflammatory disease mainly manifested by genital ulcers, oral ulcers, ophthalmia, and skin lesions. The cause of leukemia is still unclear, and it can be controlled and prevented from progressing through localized treatments, systemic medications, and surgical treatments. Local treatment is mainly for genital ulcers, oral ulcers, skin damage and other symptoms, such as the use of benzalkonium chloride, glucocorticosteroids such as prednisone, etc. In addition, systemic medication through non-steroidal anti-inflammatory drugs celecoxib, colchicine, immunosuppressants such as cyclophosphamide and other drugs. The above medications need to be taken on medical advice. Patients with aneurysm, gastrointestinal perforation, gastrointestinal bleeding, etc. need to undergo surgical treatment. It is recommended that leukemia patients go to the rheumatology and immunology department of regular hospitals for consultation and treatment under the guidance of doctors.