If you frequently feel a feeling of suffocation and discomfort in the middle of your chest, you should first rule out cardiovascular disease. Cardiovascular disease mainly refers to coronary heart disease and angina pectoris. In such people, one or more of the coronary arteries on the surface of the heart are narrowed, and if the narrowing exceeds 50%, the patient can be diagnosed with coronary heart disease. If the stenosis exceeds 70%-75%, the patient may have clinical manifestations of myocardial ischemia, including chest tightness, shortness of breath, chest pain, etc. Patients with chest tightness and chest pain should visit the cardiology department of their local hospital and first undergo an electrocardiogram when asymptomatic. If the patient has a recurrence of symptoms, another ECG should be performed to compare the two ECGs and determine whether there are any dynamic ST-T changes, and if so, the patient is highly suspected of myocardial ischemia. In addition to this, the patient should have a cardiac ultrasound to determine if the patient has structural heart disease, including whether there is an enlargement of the heart and whether there is a decrease in the ejection fraction of the heart. Patients can undergo cardiac vascular examinations, including coronary CT in the outpatient setting and coronary angiography in the inpatient setting. Both of these tests can specifically determine whether there is a blockage in the heart vessels, as well as pinpointing the location and extent of the blockage in the patient. If the patient is finally diagnosed with coronary artery disease, he or she should follow the medical prescription for lipid regulating and stabilizing treatment, antiplatelet, coronary dilation and, if necessary, stent implantation.