HIV patients who develop herpes consider that it may be herpes zoster, which is mainly caused by the patient’s immune deficiency while the herpes virus replicates in the body. Herpes zoster is a neurotropic virus and is distributed along the nerve ganglia. Herpes zoster is usually found mainly in the subcostal area and is distributed in strips along the nerves of the ribs. The blisters are painful and may become infected when they are broken. Herpes zoster is treated with antiviral drugs, and should also be treated with antiviral drugs to inhibit HIV replication as soon as possible, so that the patient’s immune function can be gradually restored.