Novel coronavirus infection does not necessarily result in persistent fever. Whether or not the disease develops after novel coronavirus infection and the severity of the disease depend mainly on the immunity of the body, whether or not it has been vaccinated, and the virulence, invasiveness, and quantity of the infecting virus. Clinically, according to the severity of the disease, it can be categorized into asymptomatic infected persons, mild cases, common cases, severe cases, and critically ill cases. For asymptomatic infected persons, they usually do not have any symptoms and do not develop fever, and mild cases show low-grade fever. Ordinary cases will develop a fever, which manifests itself as a high fever, but the fever pattern is usually irregular, and very rarely there will be a persistent fever. Severe cases and critically ill cases mostly occur in the elderly and have underlying disease, and will have a low to moderate degree of fever, sometimes without significant fever. Children infected with the virus also have mild symptoms, their body temperature does not rise significantly, and their symptoms are atypical, with only gastrointestinal symptoms such as vomiting and diarrhea. Therefore, the fever does not necessarily persist after infection with the new coronavirus, and the symptoms of fever are usually irregular.