The female epiphysis usually closes around the age of 18, with slight differences in the time of epiphyseal closure in different parts of the body, which can be as early as 13 years old or as late as 24 years old. The epiphysis has a strong influence on the growth and development of children’s bones, and there is a certain pattern in the age of appearance and fusion, with individual and gender differences. After birth and up to 8-9 years of age, the secondary ossification centers and epiphyses emerge one after another, and the epiphyseal cartilage plate, which is connected to the backbone, develops one after another. However, the bones have to mature, and the epiphyseal plate disappears completely when the epiphysis is integrated with the backbone, and bone development is completed. The epiphysis appears 1-3 years earlier in females than in males, and the fusion period appears later in those with premature appearance of the epiphysis, and the closure of the epiphysis can be observed by X-ray examination.