Parkinson’s disease usually starts insidiously and is not easily detected by patients and their families. The disease progresses relatively slowly and is characterized by gradual worsening, with a very slow onset and atypical early symptoms, such as mild tremor of the hands, reduced smile, slow movement, and muscle stiffness. The clinical manifestations often vary from person to person, and the most important clinical manifestations include motor symptoms and non-motor symptoms. As for motor symptoms: they can be manifested as four main signs: resting tremor, bradykinesia, lead-pipe-like or gear-like muscle ankylosis, and postural gait abnormalities. Such as balance disorders, lack of expression (mask face), slurred speech, swallowing difficulties, reduced joint band swing, shuffling gait, panic gait, difficulty getting up, difficulty turning over, lower case syndrome, slowing down of daily activities (using utensils, eating, personal hygiene), blepharospasm, dystonia… Motor symptoms are the basis for the diagnosis of Parkinson’s disease. Non-motor symptom aspects: are the symptoms that can accompany PD as medical advances are found. It can be manifested as cognitive dysfunction, depression, hallucination, mental disorder, loss of smell, constipation, pain, weight loss, excessive sweating, urinary disorder, postural hypotension, sleep disorder, excessive secretion of facial oil… Generally speaking, when Parkinson’s disease patients have limb tremor as early symptoms, it is easy to attract the attention of patients and their family members because of its characteristic nature, and they often go to hospital for consultation In general, when Parkinson’s disease patients have muscle stiffness or slow movement as an early symptom, they are often considered by the patients and their families as a natural manifestation of aging and do not go to the hospital, thus delaying the diagnosis. According to statistics, the time from onset to clinical diagnosis of Parkinson’s disease is usually more than 1 to 2 years.