Typical early symptoms of Parkinson’s disease Parkinson’s disease is a movement disorder with typical symptoms of bradykinesia, resting tremor and myotonicity. The slow movement is characterized by difficulty and slowness at the beginning of the activity, such as walking on the feet; resting tremor often starts from one hand and spreads to the whole upper limb, lower limb and face, mostly asymmetrical. Many patients, like Mr. Wang, have “counting bills” or “rolling pills” like tremors in their fingers at rest, and the symptoms disappear when the fingers move randomly; myotonicity refers to the stiffness of the patient’s muscles, and if it appears in the face, it is manifested by stiff expressions and little blinking, commonly known as “mask face”, and the limbs also feel heavy or without strength when moving. Olfactory hyposmia is also a typical manifestation of early Parkinson’s disease and appears 3-7 years before the motor symptoms of Parkinson’s disease. About 90% or more of Parkinson’s disease patients have olfactory hyposmia. Therefore, the Clinical Diagnostic Criteria for Parkinson’s Disease published by the International Movement Disorders Association this year lists hyposmia as one of the supporting criteria for confirming a diagnosis of Parkinson’s disease. If older adults find that they have hyposmia and also have motor retardation, resting tremor or myotonia, they should seek medical attention at the Parkinson’s Specialized Clinic at their local hospital as soon as possible to get a clear diagnosis at an early stage of the disease. Constipation, depression, and fidgeting in bed may also be related to Parkinson’s disease. In addition to loss of smell, inability to walk, and hand tremors, the typical symptoms of Parkinson’s disease in the early stages are constipation, depression, and abnormal sleep behavior. Some Parkinson’s patients become constipated 10-20 years before the onset of typical motor symptoms, while depression can precede motor symptoms by more than two decades. Data show that up to half of people with Parkinson’s disease have abnormal sleep behaviors, such as punching and kicking during sleep, some patients kick their partners out of bed, and patients have nightmares and talk in their sleep. For elderly people who have been suffering from constipation, depression and fidgeting while sleeping for years, they should pay close attention to whether they have motor delays and hand tremors, and seek medical attention as soon as they are detected. Experts point out that Parkinson’s disease can progress and worsen over time, seriously affecting a person’s mobility, thinking ability and mood. Parkinson’s disease progresses rapidly in the early stages of the disease, but slows down in the late stages. Therefore, if scientific treatment can be given at an early stage, it can not only improve the symptoms well, but also may achieve the effect of slowing down the progress of the disease, which is especially important for improving the quality of life. It was found that patients with Parkinson’s disease who started treatment within 1-3 years after the onset of the disease had significantly better self-care ability, mobility and quality of life than those who started treatment only 4-6 years after the onset of the disease.