High and low blood glucose after hemodialysis treatment for kidney failure may be related to dialysis fluid, unbalanced diet and other reasons. 1. Dialysis fluid: When hemodialysis is performed, the dialysis fluid diffuses with human blood in a concentration gradient in the dialysis machine to discharge the waste and water in the body. Usually, the sugar content and content in the dialysis fluid are very low, which can be easily discharged through dialysis, thus can lead to the decrease of blood glucose, and if it is supplemented with the high glucose treatment, then it will lead to the increase of blood glucose. Therefore, the phenomenon of high and low blood sugar will occur. 2. Unbalanced diet: After hemodialysis treatment for renal failure, patients may have symptoms of nausea, vomiting and loss of appetite, which can be caused by too little or too much food intake, which can lead to the phenomenon of blood sugar fluctuating between high and low. If abnormal fluctuation of blood glucose is found, it is recommended that the patient go to the hospital as soon as possible, complete the relevant examinations to clarify the cause of the disease and standardize the treatment under the guidance of the doctor.