With the development of society, people’s pace of life accelerates, the diet structure is also changing, many people, especially young people often appear bad breath, bloating, belching, burping, unshaped stool, bowel difficulties and other symptoms, to the hospital to do a lot of tests did not find any problems, in fact, these are intestinal flora dysbiosis caused by the trouble. Recent research shows that intestinal flora is closely related to human health, and intestinal flora dysbiosis is associated with a variety of diseases, in addition to causing gastrointestinal diseases, but also can lead to obesity, diabetes, atherosclerosis, hypertension, cancer, depression and other diseases. So if there is an intestinal flora dysbiosis, how should we regulate it? A, adjust the diet structure, promote the growth of probiotics 1, to ensure that intestinal bacteria have sufficient food intestinal flora to grow healthily must have sufficient food to ensure that these can promote the growth of beneficial bacteria food called probiotics. Prebiotics are mainly dietary fiber that cannot be digested by the body. These undigestible dietary fibers can be digested and broken down by beneficial bacteria in the intestine and become a source of nutrition for their survival. Prebiotics are mainly found in vegetables, fruits and coarse grains that are high in soluble and insoluble fiber. Vegetables are rich in vitamins, minerals, phytonutrients and soluble fiber. Therefore, vegetables are extremely important foods in a dysbiosis diet and are extremely important for adjusting dysbiosis, and it is best to eat some vegetables at every meal. However, some vegetables contain starch, it is best to eat only once or twice a week. Starchy vegetables include: potatoes, yams, etc. Non-starchy vegetables can be eaten in moderation. Non-starchy vegetables include: leeks, asparagus, zucchini, broccoli, eggplant, garlic, onions, spinach, cabbage, lettuce, cucumbers, etc. Fruits are also rich in dietary fiber, vitamins, minerals and phytonutrients, which are indispensable to adjust the intestinal flora. However, unlike vegetables, do not consume too much fruit every day because of its high sugar content. Fruits with high prebiotic content include: dates, persimmons, grapes, duck pears, apples, bananas, etc. The main prebiotic-rich coarse grains are whole grains and legumes. Whole grains are processed to retain all the important parts of the grain seed with natural nutrients, including whole wheat, millet, brown rice, purple rice, black rice, barley, oats, barley, quinoa, rye, buckwheat, sorghum, corn, barley and so on. Most whole grains contain a high percentage of insoluble and soluble fiber. Whole grains can be a nutritional supplement to your diet, but should only be consumed in moderation, about 2 to 3 times a week. Legumes are extremely rich in prebiotics in their skins. Common legumes include: soybeans, mung beans, black beans, fava beans, red beans, cowpeas, peas, cut beans, lentils, and kidney beans. Raw beans contain ingredients that the body cannot digest, so they should not be eaten raw, it is best to cook before eating. 2, supplemented with food containing probiotics eat more fermented foods, fermented foods are foods that already contain live cultures of beneficial strains of bacteria. For example, we are very familiar with: yogurt, cheese, rice wine, red wine, kimchi, sauerkraut, miso, tempeh and so on. But make sure that the food you choose is fermented and not pickled. If the food is pickled rather than fermented, then it will lose all of its prebiotic and probiotic benefits. Yogurt is best unsweetened or low-sugar yogurt. Drinking a glass of red wine every day will significantly increase the number of beneficial bacteria in the intestinal flora after four weeks, which may be related to the polyphenols in red wine, which is a powerful antioxidant. Second, adjust the regularity of life, in line with the biological clock of intestinal flora Some studies show that the intestinal flora is with the biological clock and there are periodic changes. For example, the expansion and contraction of the number of lactic acid bacteria in the intestine during the day will show regular changes over time, and the biological clock of these intestinal flora will be consistent with the biological clock of the host, so normal sleep and eating habits are necessary to maintain the rhythmic fluctuations of the intestinal flora. Once the human biological clock is disturbed, such as dietary pattern change, frequent global travel, etc., the intestinal flora will lose the rhythm, which will lead to host obesity or diabetes and other metabolic diseases. Micro-ecological agents are also called micro-ecological regulators, which can regulate the dysbiosis and maintain the balance of intestinal flora. At present, they are divided into three types internationally, namely probiotics, prebiotics and synbiotics. 1, probiotics: refers to the live bacterial preparations and their metabolites that play a beneficial role by improving the ecological balance of human intestinal flora to improve human health and health status. At present, the probiotics used in human body are Bifidobacterium, Lactobacillus, Clostridium typhimurium, Bacillus licheniformis and so on. 2, prebiotics: refers to substances that can selectively promote the growth and reproduction of one or several kinds of probiotic bacteria in the human intestine, through the increase in the reproduction of beneficial bacteria, inhibit the growth of harmful bacteria, so as to achieve the purpose of adjusting the intestinal flora and promoting the health of the body. The common ones are lactose, sucrose oligosaccharide, cottonseed oligosaccharide, isomalto-oligosaccharide, corn oligosaccharide and soybean oligosaccharide. These sugars are neither digested and absorbed by the body, nor decomposed and used by intestinal flora, but can only be used by intestinal beneficial flora such as bifidobacteria, lactobacilli, etc., so as to achieve the purpose of adjusting the normal intestinal flora. 3.Hybrid: It refers to the preparation of probiotics and prebiotics coexisting at the same time. After taking it to reach the intestinal cavity can make the probiotics that enter under the action of prebiotics, reproduce and increase again, so that it can better play the role of probiotics. Microecological preparations as drugs should be used under the guidance of a doctor, in principle, antibiotics should not be used at the same time, especially oral preparations, and in severe cases when antibiotics cannot be stopped, the dose of microecological preparations and the number of doses can be increased, and probiotic preparations can also be added. The antibiotics are a double-edged sword that can lead to dysbiosis but can also help control dysbiosis, so they must be used reasonably. If it is an overgrowth of intestinal bacteria, antibiotics are usually preferred, commonly used drugs: rifaximin, neomycin, metronidazole or tinidazole, daflucan, mycobacterium, etc. Because the process of using antibiotics, especially the application of broad-spectrum antibiotics, will kill both probiotic and pathogenic bacteria, causing serious impact on the intestinal flora and disrupting the balance of the intestinal flora. Therefore, when using antibiotics or hormones, strictly grasp the indications, it is best to do drug sensitivity tests and choose the most sensitive antibiotics. For the elderly and weak after the disease, in the antibiotics and with the use of lactobacillus or bifidobacteria live preparations to prevent intestinal flora imbalance. Fifth, serious dysbiosis can be considered fecal transplantation fecal transplantation is the healthy human fecal flora, transplanted into the patient’s gastrointestinal tract, the reconstruction of the new intestinal flora treatment. Studies have shown that fecal transplantation can prevent and treat intestinal dysbiosis. Although this method is currently an experimental treatment, as testing technology continues to advance, fecal transplantation can be applied to the treatment of more chronic diseases related to intestinal flora dysbiosis.