Three-step therapy for cancer patients is the first choice recommended by the World Health Organization to cancer patients all over the world. I have been practicing medicine for 25 years, and there are patients or their family members who ask me for “Dulcolax”, which is not recommended for cancer patients because of its weak effect and high toxicity. I will briefly introduce the “three-step therapy”: the first step of medication: non-steroidal anti-inflammatory drugs for: mild pain can be tolerated in general, can live a normal life, sleep is basically not disturbed. Representative drug: aspirin, 0.3—0.6 three times a day. The second ladder of medication: weak opioid analgesics For: moderate pain is persistent, sleep is disturbed, appetite is reduced. Representative drugs: Tramadol capsules 100 mg / times, three times a day. Codeine 10~30 mg/times three times daily Third-step program: strong opioid analgesics Applicable to: severe or intolerable cancer pain that causes serious disruption of life and sleep Representative drugs: morphine controlled-release tablets 30~60 mg/times every 12 hours, can not be taken orally can be administered rectally. It should be noted that: 1 now can be directly from the first step into the third step; 2 the second and third step can be combined with the application of any drug in any of the above steps, staggering the time of taking each drug, so that the effect is better. 3 morphine for cancer patients without extreme amount, and the effect is not capped, that is to say, only to ensure that the patient is pain-free, and other things can be disregarded; 4 the use of side effects of the drug to try to counteract. If these are not enough to relieve pain, we have more invasive or non-invasive methods to help you relieve pain. For example, there are a variety of injection therapies and neurodestructive therapies.