First, the site can be divided into pain point injection and, root block, nerve trunk block, plexus block. Pain point block is self-explanatory. Root block stem block and plexus block have a mutual substitution effect. For example, radicular sciatica can be relieved by plexus block, and plexus pain can also do epidural block. Second, the nature of physical chemical to mechanical compression and stimulation of the nerve is physical, to drug infiltration of the nerve is chemical nerve block Third, reversible irreversible semi-reversible local anesthetic block is mostly reversible, physical block can be considered semi-reversible or irreversible; nerve disrupting drug block is irreversible or semi-reversible. Fourth, the drug local anesthesia drug concentration hormone commonly used drugs are local anesthetics, steroidal anti-inflammatory drugs, nerve destroying drugs, vitamins, Chinese medicine preparations. 1, local anesthetic About the concentration problem: we know that different nerve parts and different nerve fibers require different concentrations of local anesthetic in order to block, that said, we have to make it clear that patients with chronic pain with local anesthetic is not purely for pain relief, mostly for anti-inflammatory and conditioning. (And don’t think I use local anesthetics to give the patient pain relief !) However, the concentration of the local anesthetic is still a critical part of the success of the treatment. The local anesthetic itself has a good anti-inflammatory effect as does the nerve block, which also depends on its effective concentration. If you are just doing pain point closure, a very low concentration is not a bad idea, but if you are treating a disease in which motor nerves are involved, the effect will be greatly reduced if the motor nerves are not blocked. For example, in discogenic diseases and muscle spasms, if the motor nerves are blocked and the muscles are relaxed, the recovery of the disease is facilitated, but not vice versa. And only a good nerve block can really have an anti-inflammatory effect. Imagine your local anesthetic concentration even sympathetic nerve can not block, blood vessels are still constricted, muscle spasm, blood flow can not be improved, the toxin metabolism can not be, how to say that the disease is cured? Regarding the type, any kind of local anesthetic can do nerve block, the clinical effect is no difference, master the concentration and amount. As mentioned earlier, local anesthetic, nerve block has a good anti-inflammatory effect, especially sympathetic nerve block can play the same role as steroids, and there is no steroid side effects and application of concerns, we can be liberated from the application of hormones. 2.Hormones There is no evidence to prove that the application of hormones is more effective, and many diseases can be treated without hormones. Moreover, the application of suspension in the joint cavity of the spinal canal is easy to cause the consequences of diabetes and other groups of people to be limited in the application, so it is still necessary to use sparingly or cautiously. 3, vitamins into the body is quickly metabolized, can not play a local role, to not as good as oral systemic effect. 4, Chinese medicine particles are too large, it is best not to do injection.