Tramadol, or tramadol hydrochloride tablets, and Dulcolax, or pethidine hydrochloride tablets, should not be taken at the same time. Both drugs are painkillers, taking them at the same time may inhibit respiration, patients may experience nausea, sweating and other symptoms, drug allergies are prohibited. Tramadol hydrochloride tablets belong to the morphine class of oral strong analgesics, used for a variety of acute and chronic pain pain relief treatment; pethidine hydrochloride tablets belong to the strong analgesic, suitable for a variety of severe pain. Both drugs belong to the opioid class, and taking them at the same time may lead to overdose and the adverse reaction of dyspnea. Some patients may also experience nausea, sweating, postural hypotension, and other unpleasant symptoms after using the drug. Tramadol Hydrochloride Tablets and Pethidine Hydrochloride Tablets are contraindicated in patients who are allergic to the ingredients to avoid allergic symptoms such as rare skin rashes, vomiting and shock. Tramadol Hydrochloride Tablets and Pethidine Hydrochloride Tablets should not be taken at the same time to prevent the symptoms of respiratory distress that may occur. It is recommended that patients with body pain, timely medical treatment, follow the doctor’s instructions for medication, should not be self-medication.