Daily lethargy and listlessness may be related to physiological reasons, mental diseases, endocrine diseases, blood diseases and other reasons. 1. Physiological reasons: poor rest and excessive stress can cause drowsiness and listlessness, which is a physiological phenomenon that may be relieved after enough rest and relaxation. 2. Mental illnesses: such as depression, patients will experience significant and persistent low mood, usually lasting more than two weeks, resulting in daily lethargy and listlessness. 3. Endocrine diseases: such as hypothyroidism, patients with insufficient thyroid hormones in the body, which can reduce the metabolism of tissue cells throughout the body, may feel lethargic and listless every day. 4. Blood diseases: such as anemia, due to the reduction of hemoglobin, which can lead to a decrease in the ability to transport oxygen and nutrients, may appear every day lethargy, listlessness phenomenon. It is recommended that people who are lethargic and listless every day should go to regular hospitals in time to clarify the cause of the disease and standardize the treatment under the guidance of doctors.