Pneumonia that hasn’t cleared up after 14 days of IV medication can have many causes, and the appropriate treatment for the cause. Re-bacterial culture, change medication, add medication, etc. 1. Identify the pathogen: new bacterial culture is recommended to identify the infecting bacteria for targeted medication. Pay attention to assessing the possibility of special pathogens causing the problem, such as tuberculosis and fungi. 2. Timely change of diagnosis and treatment plan. It is necessary to assess the progress of the disease in a timely manner, and adjust the therapeutic drugs and strengthen the symptomatic support according to the changes. In addition to changing the anti-infective drugs according to the pathogen, it is also necessary to pay attention to assess whether there are complications (e.g., pyothorax, lung abscess), and whether there is poor sputum drainage. 3. Others: It is also necessary to consider whether there are other causes of pneumonia, such as rheumatic immune disease combined with lung injury; whether there is drug fever, whether there are other factors leading to immunocompromise, such as HIV infection. Pneumonia 14 days bad situation is more complicated, usually have to be analyzed specifically and take appropriate measures.