Tacrolimus ointment is usually applied by taking an appropriate amount of the medicine and applying it to the affected area and covering it completely, but it should be used under the supervision of a doctor. Tacrolimus Ointment is usually used as a second-line treatment for non-immuno-compromised patients with moderate to severe atopic dermatitis who are not suitable for conventional therapy due to potential dangers and who cannot tolerate conventional therapy. Typically, it is usually necessary to apply a suitable amount of the medicine in a thin layer to the affected skin and gently rub it in so that it covers the affected skin completely. Some patients may experience adverse reactions such as burning sensation, itching, and allergy after using the medicine. It should be noted that it should be avoided in potentially worsening skin diseases and malignant skin diseases; it is contraindicated in people who are allergic to the product. If you need to use tacrolimus ointment, you need to use the medicine under the guidance of a doctor.