There are many causes that can cause pain in the big toe: first, bunions or bunions, which can cause pain and swelling in the bunion or metatarsophalangeal joint, as well as painful limitation of movement. Second, gouty arthritis. Gouty arthritis causes pain, swelling, and redness in the big toe after local damage and the formation of gouty crystals. Then, other arthritis, such as rheumatic or rheumatoid arthritis, can also invade the bunion and cause localized pain in the bunion. Finally, specific arthritis, such as reactive arthritis, can also cause increased inflammation in the bunion, resulting in localized pain, swelling, and functional limitations. Once the pain is present, it is necessary to go to the hospital to rule out metabolic diseases.