The peculiarities of children’s physique make many drugs that are used for adults no different from those used for children, but should never be used! The following drugs, please ask the parents to polish their eyes. 1, tetracycline drugs tetracycline drugs can cause enamel dysplasia, tooth coloring yellowing and bone growth inhibition, so children under 8 years old is prohibited. These drugs are: tetracycline, hygromycin, doxycycline (doxycycline), minocycline (methomycin), guanocycline, demeclocycline, metacycline, etc. 2, quinolones These drugs can cause damage to the bones and joints of young dogs and other mammals, especially the cartilage tissue of weight-bearing bones and joints, so it is prohibited for minors under 18 years of age. Many of these drugs, commonly used are norfloxacin, ciprofloxacin, ofloxacin, levofloxacin, etc.. 3, corticosteroids These drugs can mask the symptoms of inflammation, but also can cause endocrine dysfunction, in general, should try to avoid the use of adrenal corticosteroids, such as cortisone, prednisone (prednisone), dexamethasone, etc.. Androgens such as methyltestosterone, testosterone propionate and other long-term application will cause premature closure of the skeleton, affecting the growth and development of children, especially in children suffering from chickenpox should be prohibited. 4, antipyretic and analgesic drugs compound preparations containing pyrazolone, such as aminophenazone tablets, anandamide, painkillers, disulfiram tablets, etc., its antipyretic and analgesic effect is certain, but children should not be used continuously, it is easy to cause aplastic anemia and purpura. Another example is the use of aspirin or aspirin-containing preparations in newborns can easily lead to Reye’s syndrome (a common acute brain disease with a death rate of up to 50%). Aspirin can also damage the auditory nerve in infants and children. Diclofenac sodium, one of the main ingredients of FluTone, is likely to cause hematuria when taken by children and should not be used as a common medicine for children with colds and is prohibited for children under 3 years old. Diclofenac sodium extended-release tablets are also not recommended for children and adolescents due to the high dose (75mg per tablet). Acetaminophen is also the most widely used antipyretic analgesic, its efficacy, oral absorption is rapid and complete, but it should be noted that the use of doses should not be large, children under 3 years of age should be used with caution. 5, aminoglycosides such as streptomycin, gentamicin, minomycin, amikacin, cisomicin, etc., continuous use is likely to cause damage to the auditory nerve and renal function in children, children under 6 years old is prohibited. 6, antidiarrheal drugs compound difenoxin (compound phenylephrine), suitable for acute and chronic functional diarrhea and chronic enteritis treatment. Each tablet contains 2.5mg of diphenoxylate and 0.025mg of atropine sulfate, of which diphenoxylate acts similar to morphine on the intestinal tract and can act directly on the intestinal smooth muscle. Since there are reports of pediatric poisoning and even death caused by the application of this drug at home and abroad (the deaths are concentrated in infants and children less than 2 years old), and since there is no unified standard for the dosage of this drug for children, it is prohibited for infants and children under 2 years old, and should be used with caution for children over 2 years old (strictly control the dosage of the drug). Loperamide (Emmenthal) is suitable for the treatment of acute and chronic diarrhea caused by various etiologies. However, its effect is stronger and faster than that of difenoxanthine, and its use in younger children is likely to cause adverse drug reactions, such as affecting the central nervous system, etc. In addition, there have been reports of deaths in newborns, so its use in younger children is restricted at home and abroad. Medicinal charcoal can adsorb a variety of toxic and non-toxic irritants that cause diarrhea and abdominal discomfort, reduce the stimulation of the intestinal wall, reduce intestinal peristalsis, and thus play a role in stopping diarrhea. But because the drug adsorption is strong and non-selective, the growth activity of digestive enzymes such as pepsin and pancreatic enzymes are affected, long-term application can cause malnutrition in children, so the long-term application of children under 3 years old is prohibited. 7, deworming medicine Intestinal parasitic diseases (such as roundworms, pinworms, etc.) are very common in children, especially in rural areas of China, almost 95% of children have different degrees of infection. Therefore, it is necessary for children to have regular stool tests to find out whether there are parasites in their bodies and what kind of parasites they have. Some parents think that their children have worms when they find that their children are yellow and thin and have a poor appetite, so they blindly take deworming medicine and then take it again after not seeing the discharge of worms, which affects the health of their children. There are many kinds of deworming drugs, some of which are effective for a variety of parasites, while others are effective for only a few. Commonly used deworming drugs include albendazole (intestinal wormer), piperazine (roundworm repellent), thiacil (anthelmintic), levamisole, mebendazole, neem bark, umeboshi, and monkshood. These drugs have certain toxicity and side effects, such as albendazole and Ascaris lumbricoides, although low toxicity, but regular consumption or overdose can cause dizziness, headache, vomiting and liver function damage, so the drug instructions specify that children under 2 years of age are prohibited. Neem bark is bitter and cold, and can cause death by poisoning in excess. 8, anti-infective drugs such as sulfonamides, furantoin, furazolidone, chloramphenicol, neomycin can make newborns appear hemolysis, gray baby syndrome, hyperbilirubinemia, so newborns are prohibited. According to the drug instructions: cefixime, not suitable for infants and children under 6 months; tinidazole injection, prohibited for children under 12 years old; ornidazole injection, not suitable for children under 3 years old. 9, antacids H2 receptor antagonists such as cimetidine, ranitidine, famotidine, etc. continuous use of pediatric liver, kidney function, hematopoietic system and endocrine system have certain damage, so children under 16 years of age should not be used. Diphenhydramine hydrochloride, teicoplanin, and diphenhydramine hydrochloride are prohibited for infants and children under 6 months of age. Cetirizine, which is prohibited or contraindicated in children under 6 years of age. In conclusion, children are in a period of continuous growth and development in terms of physical and organ functions, and with the increasing number of drugs, the safety of medication is being paid more and more attention to the correct selection of drugs and their rational use to ensure the safety of medication for children and care for the healthy growth of the next generation is an issue that pediatricians and pharmacists should pay attention to.