Amino acid deamination is the process of amino acid deamination under the action of deaminase to generate α-keto acid. There are oxidative deamination, transamination, combined deamination and non-oxidative deamination. 1. Oxidative deamination: it refers to the process of amino acid dehydrogenation and amino acid removal under the catalytic action of deaminase. 2. Transamination: It refers to the process of transferring the amino group of α-amino acid to another α-keto acid catalyzed by transaminase to produce the corresponding α-keto acid and a new α-amino acid. 3. Combined deamination: This refers to the combination of transamination and oxidative deamination of glutamate to convert amino acids into ammonia and the corresponding α-keto acids. 4. Non-oxidative deamination: some amino acids can be deaminated by non-oxidative deamidation, such as the presence of another amino acid deamination reaction in muscle, which can be deaminated by the purine nucleotide cycle. Amino acid deamination, plays a very important role in the human body.