Congenital dyskeratosis syndrome, also known as zinssers syndrome, is a recessive genetic disorder that is an extremely rare congenital anomaly. Congenital dyskeratosis, also known as zinssers syndrome, is a hereditary disorder that is predominantly seen in males and develops in childhood. The clinical manifestations of congenital dyskeratosis include: 1. Fine reticular pigmentation on the skin surface, mainly on the face, neck and chest and back. 2. Malnutrition-like changes in the nails, such as nail deformation. 3. Leukoplakia of the oral mucosa, which may be located bilaterally on the buccal mucosa and the dorsum of the tongue, and recurrent blisters or ulcers may occur. There is no specific treatment for congenital dyskeratosis, and the main treatment is to give laser treatment or cryotherapy to improve the symptoms, and the specific conditions must strictly follow the doctor’s instructions.