Men’s pubic blisters are commonly associated with genital herpes, and some of them can also be seen in herpes zoster involving the genital area and lead to. 1. genital herpes: a common sexually transmitted disease, mainly caused by herpes simplex virus infection of urogenital and perianal skin mucosa, can lead to blisters, pain and itching in the genital area of the patient, and other discomfort. 2. Herpes zoster: is latent in the body of chickenpox – herpes zoster virus, after reactivation and caused by skin damage, mainly manifested as a band-like distribution of clusters of blisters, accompanied by local pain. If herpes zoster involves the genital area, it can also lead to blisters in the man’s pubic area. Men with long blisters in the pubic area had better go to the hospital in time, under the guidance of the doctor for reasonable treatment.