The rotation of the eyeballs during sleep is a completely normal physiological phenomenon. During sleep, most areas of the brain are at rest, but not the entire physiological functions of the body are in a state of complete rest, there are still many cells in the nervous system that are still active, so the extraocular muscles responsible for eye movements during sleep are innervated by active nerve cells and form eye movements, which can be divided into two different states of REM sleep and non-REM sleep The two states can be divided into REM sleep and non-REM sleep. In REM sleep, the nerve cells in the brain are more active, which stimulates the contraction of the extraocular muscles, resulting in eye movements, accompanied by dreaming, etc. Therefore, eye rolling during sleep is a normal physiological phenomenon, not a disease and does not require treatment.