If diabetes is diagnosed, pioglitazone metformin tablets may need to be taken for a long period of time with regular monitoring of blood sugar. Pioglitazone Metformin Tablets are a combination of insulin sensitizers and biguanides. It is used for the treatment of type 2 diabetes mellitus in patients who do not respond well to treatment with metformin hydrochloride alone and in patients who need to be treated with a combination of pioglitazone hydrochloride and metformin hydrochloride. Diabetes mellitus is a chronic disease, usually can not be cured, need long-term medication, so if taking pioglitazone metformin tablets to lower sugar effect is good, should be long-term regular medication. And need to monitor blood sugar, according to the blood sugar level adjustment of medication. Common adverse reactions to the drug are upper respiratory tract infections, diarrhea, urinary tract infections, edema and headache. Contraindications include severe heart failure, renal dysfunction, known hypersensitivity to the components of pioglitazone and metformin, acute or chronic metabolic acidosis. The medication should be taken under the supervision of a physician, and blood glucose, liver function, renal function, and weight gain should be monitored during administration. If there are serious adverse reactions, it is necessary to consider reducing the dosage or changing to other drugs. Pioglitazone Metformin should be used reasonably under the guidance of a doctor according to the specific condition, and should not be applied without authorization to avoid adverse consequences.