If an allergic reaction occurs during the course of taking anti-tuberculosis drugs, the decision on what to do depends on the specific situation. For mild allergic reactions, such as skin rashes, itching and low fever, you can stop taking the anti-tuberculosis drugs for the time being and take some anti-allergic drugs, such as loratadine, paracetamol and diphenhydramine, and observe whether the skin rashes subside and the body temperature is normal. If these allergic reactions disappear, you can continue to take anti-tuberculosis drugs. For severe allergic reactions, such as persistent high fever and anaphylactic shock, it is necessary to stop all anti-tuberculosis drugs and add drugs one by one after the body temperature is normalized, so that the allergy can be screened out to find out which kind of drug is causing the allergy. Blood can also be drawn to test which component of the anti-tuberculosis drug the blood is allergic to, so as to screen out the combination of non-allergic drugs and find out a reasonable treatment plan.