Bismuth capsule is a kind of gastric mucosa protector, which can protect gastric mucosa and kill Helicobacter pylori, its side effects are mainly that bismuth can be absorbed through blood, if taken for a long time, it will lead to abnormal liver function and kidney function, so before using bismuth preparation, we must ask the patient whether there is kidney function disease, if there is abnormal kidney function problem, bismuth preparation is strictly prohibited. It may also cause transient liver function abnormality, so the use cycle of bismuth capsules should not be too long, usually not more than 8 weeks of continuous use, and before use, ask the patient in detail whether there is any liver and kidney function disease, otherwise it will not be used. Some patients may experience nausea and constipation when using bismuth capsules, which can be relieved after stopping the medication, and bismuth capsules can also cause dark stools, so we should communicate with patients before using the medication.