The main causes of scleritis ophthalmica include autoimmune diseases, connective tissue diseases, metabolic diseases, and infectious factors. Scleritis is associated with autoimmune diseases and connective tissue diseases, such as rheumatoid arthritis and systemic lupus erythematosus. And metabolic diseases, such as gout, can also increase a patient’s risk of suffering from scleritis. Scleritis can also be caused by trauma or chemical injury to the patient’s eye, secondary to infection by pathogenic bacteria such as bacteria and viruses. In addition, systemic infectious diseases, such as syphilis and herpes zoster, can also involve the eye locally, and inflammation of tissues near the sclera, such as the cornea, conjunctiva, uvea, or in the orbit, can spread directly to the sclera and cause scleritis. It is recommended that patients with scleritis seek prompt medical attention to evaluate the condition and follow the doctor’s instructions for treatment.