The constant grumbling of the stomach is a manifestation of increased intestinal peristalsis, which may be caused by physiological factors, acute gastroenteritis, hyperthyroidism and other reasons. It can be treated through general treatment, taking medication and so on. 1. Physiological factors: such as increased secretion of gastric acid and other digestive juices in the case of starvation, increased intestinal peristalsis, there will be the phenomenon of stomach grumbling, after eating this phenomenon will be reduced. 2. Acute gastroenteritis: gastrointestinal bacterial infection, local inflammation stimulation leads to increased gastrointestinal peristalsis, causing stomach grumbling, can also be accompanied by abdominal pain and diarrhea symptoms. You can take amoxicillin, cefoperazone, levofloxacin and other anti-infective treatment as prescribed by the doctor. 3. Hyperthyroidism: hyperthyroidism patients thyroid hormone increase, resulting in an increase in metabolism, hyperfunction of the system, the digestive system is no exception, there will be an increase in intestinal peristalsis, resulting in the symptoms of the stomach grumbles and grunts. You can take methimazole, propylthiouracil and other anti-thyroid drugs as prescribed by the doctor. There are other reasons why your stomach is always grumbling, you should go to the hospital in time, complete the examination, and then give targeted treatment after the cause is clear. The above drugs should be used under the guidance of a doctor.