Herpes on hands may be caused by herpes sweat, chickenpox, hand, foot and mouth disease and other diseases. 1. Sweat herpes: Sweat herpes is a blistering skin disease that occurs on the hands and feet, and the cause is related to allergies, dermatophyte infections, and mental factors. The attack starts with itching and itchy blisters will appear on the palms of the hands, soles of the feet and fingers. 2. Chickenpox: Chickenpox is caused by varicella zoster virus infection, patients will initially appear red spots, papules and other rashes, after a few hours, the localization will become fluid-filled herpes, centripetal distribution, usually accompanied by pain, can appear on the hands. 3. Hand, foot and mouth disease: Hand, foot and mouth disease is an acute febrile rash infectious disease caused by enteroviruses, with scattered papules and herpes on the hands, feet, mouth and other parts of the body, which can be transmitted through the digestive tract, the respiratory tract, and close contact. There are many causes of herpes on the hands, so it is recommended to consult a doctor for a clear diagnosis.