Spleen enlargement can benefit from aerobic exercise such as walking, but physical activity will not normalize spleen enlargement. The treatment should be based on the cause of splenomegaly. 1. For congenital splenomegaly, if there is no abnormality in the laboratory test results and imaging test results, no treatment can be done, and reasonable diet and appropriate exercise can be maintained. 2. If the splenomegaly is caused by infection, such as typhoid fever, the patient should rest in bed, avoid strenuous exercise, and the enlarged spleen will recover on its own after active anti-infection treatment. 3. If the splenomegaly is caused by non-infectious factors such as cirrhosis of the liver, it is generally more difficult to recover, and some aerobic exercise such as walking, swimming, Tai Chi, etc. can be done appropriately, which is beneficial to your health. If you find unexplained splenomegaly, it is recommended to actively improve the examination, clarify the cause of the disease, and standardize the treatment and exercise under the guidance of the doctor.