Ankle pain and numbness may be due to the following reasons: First, lumbar disc herniation, lumbar disc herniation can appear numbness and pain in the ankle after compression of the nerve root, often caused by the 4th-5th lumbar disc herniation, which should be diagnosed by lumbar spine’s CT and MRI. Second, lumbar spinal stenosis, lumbar spinal stenosis can also compress the nerve root, resulting in ankle pain and numbness. Third, pyriformis syndrome, when pyriformis syndrome is severe, it compresses the sciatic nerve, which can also cause pain and numbness in the ankle. Fourth, peripheral nerve compression, when the peripheral nerves innervated by the ankle nerve compression, such as tumor compression, trauma and other scar adhesion, fracture stimulation, can also appear at the ankle numbness, this time to carry out relevant physical examination and electromyography for diagnosis.