The three shots of the Septavalent are about $3,000-5,000 and can be given at ages 9-45. Nine-valent refers to the nine-valent human papillomavirus (HPV) vaccine. The cost of three doses of the nine-valent HPV vaccine may vary in price in different regions and organizations, and the overall cost is about $3,000-$5,000, and you need to consult with the vaccination organization. The nine-valent HPV vaccine needs to be vaccinated three times, according to the immunization program of 0, 2, 6 months. The vaccination usually needs to be completed within one year. The risk of exposure to HPV increases with age, especially with the onset of sexual activity, so early vaccination is recommended. HPV vaccination is contraindicated in persons who have had a hypersensitivity reaction to the active ingredient of the vaccine or to any of the excipient components, and persons who have symptoms of hypersensitivity after injection of the product should not be revaccinated with the product. Regular cervical cancer screening is still required after HPV vaccination.