Chronic obstructive pulmonary resting state finger oximetry oxygen saturation 90, a little bit of activity rapid decline wheezing uncomfortable, consider the condition is more serious or in acute exacerbation, need to consult a doctor in a timely manner to assess the condition of the standardized treatment, the treatment method includes general treatment, drug therapy, and so on. 1. General treatment: smoking cessation, adequate rest, oxygen therapy support, nasal cannula oxygen for mild cases, and non-invasive ventilator or endotracheal intubation for severe cases. 2.Drug treatment: (1) Bronchodilators: long-acting and short-acting β2-adrenoceptor agonists such as salbutamol, formoterol, anticholinergics such as ipratropium bromide aerosol, theophyllines such as aminophylline. (2) Expectorants: e.g., Ambroxol hydrochloride, Carbocisteine, can be applied to those who cannot easily cough up phlegm. (3) Glucocorticosteroids: including intravenous glucocorticosteroids such as methylprednisolone, inhaled glucocorticosteroids such as budesonide to improve symptoms. (4) Antimicrobial therapy: bacterial infection is often combined with acute exacerbation of chronic obstructive pulmonary disease, and sputum culture should be taken and antimicrobial therapy, such as intravenous drip ceftazidime and meropenem, should be given if the infection is combined. Considering the seriousness of the disease at this time, it is recommended to consult the doctor in time, and the specialist will make and adjust the treatment plan after fully evaluating the disease, so as to avoid delaying the disease.