Ear pain during a cold is usually caused by infectious factors. When you have a cold, you are particularly susceptible to bacterial, viral and fungal infections, and when you blow your nose, the pressure in the mucous membrane of the nose is too great, which can cause retrograde infections around the ear and lead to ear pain. When severe sinusitis occurs during a cold, the sinus infection will retrogress to the tympanic membrane, leading to otitis externa and otitis media, which will also cause the clinical symptoms and manifestations of earache. When you have a cold, your body releases inflammatory factors, such as interleukin-2, interleukin-4, interleukin-6, leukotrienes, prostaglandins, bradykinin, etc. Such inflammatory factors can lead to abnormal sensitization of the body’s nerve roots, and pain can occur, especially in the ear where the nerve endings are more sensitive. In infections prone to trigeminal neuritis and facial neuritis, will also be self-conscious ear pain is relatively obvious.