No clinical studies have shown that reduced dopamine causes neurasthenia. The etiology and pathogenesis of neurasthenia have not been conclusively determined, and most are related to mental states or psychological factors. Decreased dopamine may be related to depression. Neurasthenia is a kind of neurosis with weak brain and body functions, mainly manifested as patients often feel lack of energy, depression, can not use the brain, limb weakness and other symptoms. Currently, it is mostly believed to be related to factors such as long-term emotional tension and excessive mental stress. Dopamine lowering may be related to depression, patients lose the feeling of happiness, can’t interest in the things that used to be interested in, low mood. It is recommended that patients with lowered dopamine should seek timely medical attention and active treatment. Neurasthenia patients are recommended to psychotherapy, for patients with anxiety, depression, sleep disorders and other symptoms can use the corresponding drug therapy. Daily attention should be paid to maintain a relaxed mood, avoid bad emotions.