Cranium is an important bone, not only about image and beauty, but also about health. If a person’s skull is sunken, it will not only be unattractive, but will also bring some other physical hazards if left untreated for a long period of time. Because under the external protection of the skull, the brain tissue can function and work normally, without the protection of the skull, danger may occur at any time. Can a depressed skull be leveled out again? It depends on the specific case and is treated by a specialized neurosurgeon. In severe cases, surgery may be required to remove part of the bone flap, which leaves a defect in the skull that requires cranial repair at a later stage to restore the flatness. However, when doing cranial bone repair surgery, the key point is the choice of materials, good materials to achieve more ideal repair results. Currently, many hospitals use titanium mesh material for skull repair. Titanium mesh material has made some progress compared with some earlier materials, but there are still some shortcomings and defects, such as postoperative rejection, possible infection, affecting postoperative examination, and exposure of the material, etc. Our team uses a new type of polymer mesh material, which is a polymerized polyurethane material. Our team used a new polyether ether ketone PEEK material to operate on patients. This is an advanced polymer material that is very stable in all its properties and is almost comparable to autologous cranial bone. Moreover, the team has carried out more in-depth research and exploration, continuous technical innovation and upgrading, introduced the concept of aesthetic plastic surgery in the operation, and comprehensively carried out PEEK cranial bone repair plastic surgery, which makes the repair effect more natural and beautiful.