The thumb is a little numb. First, the first consideration is peripheral neuropathy, and exposure to toxic substances, such as organic phosphorus, pesticides, etc., if necessary, you can check the electromyography to confirm the diagnosis. For numbness caused by peripheral neuropathy, it is recommended to take oral nerve-nourishing drugs, such as methylcobalamin or vitamin B12; second, numbness in the thumb can also be seen in local compression, such as carpal tunnel syndrome, due to compression of the radial nerve, which can cause numbness in the thumb, if necessary, consult an orthopedic surgeon to give local release treatment; third, numbness in the thumb can also be seen in Cervical spondylosis, due to the protrusion of cervical discs, resulting in nerve root compression, the patient can appear numbness, and in severe cases, there will be numbness of both upper limbs, which can be reduced after neck activities; fourth, a little numbness in the thumb can also be considered cerebrovascular disease, for cerebrovascular disease caused by numbness, but also accompanied by other symptoms of neurological deficits. For example, dizziness, headache, speech stupidity, etc., if necessary, you can check the head CT or nuclear magnetic examination.