Allergic reaction to the mask may occur quickly, with burning and itching discomfort while applying the mask, and redness and rash after removing the mask, considering that the rash may be caused by the irritation of certain substances on the mask. Redness, itching and rash may appear only 2-3 days after removing the mask, at this time it is considered to be caused by the presence of allergies to certain ingredients in the mask, and a patch test is needed to help clarify the diagnosis. If an allergic reaction occurs after using the mask, avoid using it again. Local saline or boric acid solution can be used as a wet compress, and topical butyl hydroxy acid cream can be applied to the skin lesions twice a day.