Semen liquefaction takes about 15-30 minutes, and the exact time is not an accurate determination. The time for semen liquefaction is generally the time it takes for semen to fully liquefy after it is discharged, which is usually about 15-30 minutes, but in some people, semen liquefaction takes longer and may take about an hour. Every man’s body is different, so the time it takes for semen to liquefy is also different. If the time needed for semen liquefaction is longer or the semen does not liquefy, you need to be alert to the fact that it is caused by a disease. Clinically, prostatitis, seminal vesiculitis and other diseases may lead to prolonged liquefaction of semen or symptoms of non-liquefaction of semen. If there is any abnormal reaction, it is best to actively consult a doctor for examination, and follow the doctor’s instructions for treatment.