Timosartan Tablets 40 mg can be taken twice, but the daily dosage of timosartan tablets should not exceed 40 mg in people with mild or moderate hepatic impairment. Timosartan tablets belong to the ARB class of antihypertensive drugs and are used to treat essential hypertension. The antihypertensive efficacy of Timosartan Tablets is related to the dosage, the initial dosage is 40mg each time, once a day, if the drug does not achieve the desired blood pressure can increase the dose, the maximum dose of 80mg, once a day. It should be noted that timosartan tablets are mainly excreted through the bile, and its clearance may be reduced in patients with biliary obstructive disease or hepatic insufficiency. The daily dosage of this product should not exceed 40mg in patients with mild or moderate hepatic impairment, and timosartan tablets should not be used in patients with cholestasis, biliary obstructive disease, or severe hepatic dysfunction. It is contraindicated in patients who are hypersensitive to the active ingredient or any excipient component of the product; women in mid- to late-term pregnancy (during the middle and last trimester of pregnancy); patients with biliary obstructive disease; and patients with severe hepatic impairment. Concomitant use of this product and aliskiren in patients with diabetes mellitus or renal insufficiency (glomerular filtration rate (GRF) <60 ml/min/1.73m2) is not allowed. Timosartan tablets are antihypertensive drugs that carry a risk of hypotension and should be taken under the supervision of a healthcare professional and blood pressure should be monitored while taking them.