Three-year-old children coughing at night can be seen in cough variant asthma, respiratory infections, etc. Interventions need to be selected according to the cause of the disease, such as rhinitis in children can be local nasal spray, nasal irrigation, etc.. 1. Cough variant asthma: these children have increased airway responsiveness, often at night, coughing, less sputum, coughing is more intense, the use of antibacterial drugs is usually ineffective. Treatment requires avoidance of allergens and standardized nebulized therapy, often using inhaled glucocorticoids such as budesonide. Oral leukotriene receptor antagonists, such as montelukast, can be used to reduce airway responsiveness. 2. Respiratory tract infections: such as bronchopneumonia caused by Mycoplasma pneumoniae infection, there may be severe cough at night, which may be accompanied by fever symptoms, and Mycoplasma pneumoniae antibody test and chest X-ray may assist in the diagnosis. Treatment should actively use macrolides (such as azithromycin) anti-infective treatment, for severe cough need to use inhaled glucocorticosteroids (such as budesonide) nebulization, and can be taken orally to alleviate the cough symptoms. 3. Sinusitis: these babies are often combined with rhinitis, nasal secretions can be due to the backflow of cough symptoms, sometimes nighttime cough, often accompanied by nasal congestion, runny nose, etc., the duration of the disease is longer. Treatment requires the use of nasal glucocorticoids, such as mometasone furoate for local nasal spray, saline rinse nasal cavity, the use of antibacterial drugs (such as amoxicillin) as appropriate anti-infection treatment. A three-year-old child coughing at night may be due to a number of reasons, it is recommended to consult a doctor to clarify the cause of the disease. All of the above medications should be used under the supervision of a physician and evaluated by a specialist for appropriate treatment.