Hyperhomocysteinemia is a condition characterized by elevated homocysteine in the blood. Hyperhomocysteinemia is a condition characterized by elevated homocysteine in the blood, usually defined as homocysteine >15 μmol/L. Hyperhomocysteinemia does not usually present as a symptom in adults, but it increases the risk of cardiovascular disease, cerebrovascular disease, cognitive impairment, and osteoporosis-related fractures. Treatment of hyperhomocysteinemia can be achieved by eating foods containing vitamin B, folic acid, and medications containing vitamin B6, vitamin B12, and folic acid. Hyperhomocysteinemia should be treated with medication under the supervision of a doctor.