If you are taking medroxyprogesterone acetate and still bleeding, it may be the wrong time to take the medicine or the wrong program to take the medicine. 1. The wrong time to use the drug: if you use the drug when the endometrium is thicker or has begun to fall off, at this time the endometrium blood vessels have been filled, and there is no way to stop the endometrium from falling off by taking medroxyprogesterone acetate tablets, so it will be manifested in the case of bleeding while you are taking the drug. If bleeding occurs while taking the medicine, you need to stop taking the medicine and let the endometrium fall off completely. 2. Wrong medication plan: if the uterine fibroids, adenomyosis and other diseases due to uterine contraction abnormalities caused by bleeding; endometrial inflammation pathogen infection of the endometrium caused by bleeding; endometrial malignant lesions, malignant tumor cells invasion of the endometrium caused by bleeding, did not target the primary cause of the disease for treatment, it will be taking the medicine still bleeding situation. If you still have vaginal bleeding after taking medroxyprogesterone acetate, it is recommended that you visit the hospital in time to complete the examination and assess whether the medication is correct before treatment, and it is not recommended that you use the medication on your own.