Dry and flaky lips may be related to factors such as insufficient daily water intake, and to a lesser extent may be related to diseases such as lipitis and xerostomia. 1. Physiological factors: physiological factors such as insufficient or low water intake may trigger dry and flaky lips. 2. Lipitis: usually manifested as dry lips, peeling, crusting and other symptoms, the cause of its formation is not yet clear, may be sun exposure, climate change, local irritation and other factors. 3. Keratitis: the etiology of keratitis is more, may be related to infection, trauma and vitamin deficiency and other factors. Clinical manifestations for the corners of the mouth area congestion, redness, swelling, cracking and red lips dry cracking and flaking and other symptoms. There are more reasons for dry and flaky lips, and after excluding physiological factors, patients are advised to seek medical examination to clarify the cause.