There is no absolute which is better, the two are two different drugs, the essence of which are sartan antihypertensive drugs and calcium channel blockers. 1. Sartan antihypertensive drugs: ali-sartan ester belongs to the sartan class of antihypertensive drugs, its essence is angiotensin II receptor antagonist, mainly for mild to moderate essential hypertension, hypertension combined with proteinuria, diabetic nephropathy combined with hypertension. Contraindications include renal artery stenosis, patients with hypovolemia, and patients with hepatic or renal insufficiency. 2. Calcium channel blockers: their indications are hypertension and angina pectoris, and their contraindications are allergy to dihydropyridine antagonists. The specific use of which drug is the best, need to be under the guidance of a professional physician medication. It is recommended to choose antihypertensive drugs under the guidance of a physician.