Brainstem gliomas account for 1.4% of intracranial tumors. They are mainly neurogliomas, of which astrocytoma and polarized glioblastoma are more common, followed by oligodendroglioma, ventricular meningeal glioma and medulloblastoma. In addition, hemangiomas, cysts, teratomas, tuberculomas, and metastatic tumors can also be seen. It is common in children and adolescents, especially the highest incidence in children aged 5~9 years old. 1.Headache: Most of the headaches are caused by increased intracranial pressure. Glioma growth gradually increases intracranial pressure, compression, and involves intracranial pain-sensitive structures, such as blood vessels, dura mater and some cranial nerves, and produces headache. Most of them are throbbing pain, distending pain, and the parts are mostly in frontotemporal or occipital part, and in one side of the cerebral hemisphere superficial tumor, the headache can be mainly in the affected side, and the headache starts to be intermittent, and occurs in the early morning, and with the development of the tumor, the headache will be aggravated gradually, and the duration will be prolonged. Vomiting is caused by the stimulation of medulla oblongata vomiting center or vagus nerve, which may be followed by nausea and then vomiting, which is jetting. In children, headache is not significant due to separation of cranial sutures, but vomiting is more prominent due to tumors in the posterior cranial fossa. Diplopia is due to the increase of intracranial pressure, which produces optic papilla edema, and causes secondary atrophy of optic nerve and vision loss for a long time. Tumor compression of the optic nerve produces primary optic nerve atrophy, which may lead to vision loss. The adductor nerve is easy to be pressed and squeezed, which often leads to paralysis and diplopia. Epilepsy: A part of glioma patients have epileptic symptoms, and can be early symptoms. Epilepsy begins in adulthood and the latter is usually symptomatic, mostly due to brain tumor. If it is not easy to be controlled by drugs or the nature of seizure is changed, the presence of brain tumor should be considered. Those with tumors adjacent to the cortex are prone to epilepsy, and limited epilepsy is of locoregional significance. In addition, some tumors, especially those located in the frontal lobe, may gradually develop psychiatric symptoms, such as personality change, indifference, decreased speech and activity, lack of concentration, memory loss, lack of concern for things, and lack of neatness. The local symptoms are according to the location of the tumor, and the symptoms will be aggravated progressively. Especially malignant glioma grows faster, infiltrates and destroys the brain tissue, and the surrounding brain edema is also significant, so the local symptoms are more obvious and develop faster. In the early stage of intracerebroventricular tumors or tumors located in the quiet zone, there may be no local symptoms. Tumors in the brainstem and other important functional parts of the brain appear local symptoms in the early stage, and the symptoms of increased intracranial pressure appear only after a long time. In some tumors with slow development, symptoms of increased intracranial pressure often do not appear until the late stage due to compensatory effects.